The Science Behind Splash

Splash Nano is the brainchild of NanoTechnology enthusiast and expert Kalon Baird.  The desire to create infused beverages sparked a technology platform for making cannabinoids much more effective and bioavailable.  Borrowing research from the big food and pharma space, a proprietary, safe delivery platform was born. This technology can also be used to enhance and deliver other bioactive molecules as well. 

WHAT DOES NANO MEAN AND IS IT IMPORTANT?

Nano  simply means that the particles are much smaller than particles delivered through a Micro, or Macro suspension.  To put things into perspective, a human red blood cell is approximately 5,000 nanometers. Infused by Epic particles are under 50 nanometers, that’s 100x smaller.  When the same amount of CBD is broken down to such a small particle size, the surface area increases exponentially.  More surface area means more potential for bonding at the ECS receptor sites. Pretty simple common sense understanding.  Nano emulsification is one method to make particles really small, and remain small while suspended in an aqueous (water) medium.  The surface active modifiers used in the formulation must be non toxic, and able to achieve high shelf stability without creaming or sedimentation (separating), especially when dissolved in a beverage or infused in food.

BIOAVAILABILTY

Bioavailability is defined as  “The proportion of a drug or other substance which enters the circulation when introduced into the body and so is able to have an active effect.”  THC is classified by the biopharmaceutical class system as a Type 2 drug which exhibits poor aqueous solubility and high permeability. One of the main disadvantages of such “drugs” is that they need careful formulation to avoid being degraded, metabolized, and cleared by the digestive system and first pass metabolism (liver) before being absorbed.   As many as 70% of drugs on the market today fall into this classification of exhibiting poor aqueous solubility. 

The mainstream Cannabis Industry focuses on oil based delivery formulations, which are grossly archaic in the pharmaceutical and medical field.  Many companies and consumers have never heard of bioavailability, and are unaware that up to 70% of the THC they are taking is being cleared by the body before ever making it into the bloodstream.   Splash Nano uses cutting edge and proprietary technology borrowed in parts from food and Pharma sectors to deliver industry best practices for enhanced drug delivery. The future of the Cannabis Industry will be built on the platform of enhanced therapeutic delivery systems.  

PRECISION DOSING

Nano emulsions offer customizable concentrates  with active drug loading to meet the end products’ needs.  An example of this would be Splash Nano’s  standard emulsion which is able to load 10mg of Nano CBD into 5 milliliters (ml) of water.  This can be diluted into a beverage easily and uses a minimum of excipient ingredients.  

INGREDIENTS

Splash Nano proudly uses only clean label natural ingredients.  Many companies use synthetic ingredients to achieve homogeneity.  We don’t use artificial colors which have been proven to be harmful e.g. red40, blue 1,2 etc.  We use food grade GRAS ingredients to coat the precious cannabis molecules in our water soluble suspensions.  We are also vegan, allergy free and use organic ingredients. This translates to compatibility with many sensitivities which exist in today’s marketplace, and high consumer confidence.

PRODUCT CHARACTERISTICS: Color, Taste and Stability                                                      

Our suspensions will have a clear to translucent appearance. This measurement is known as the polydisperse index (PDI) and is a measurement of optical clarity. Our nanoemulsions rank under 0.2 which is ultra clear.  This value is also a “sniff test” of particle size. The smaller a particle is, the less it will scatter light, which produces turbidity or cloudiness. When you incorporate Splash Nano into your drinks, there will be no optical change perceptible. 

Just as the effects of Nano are amplified, so is the taste.  By working with source materials such as full spectrum extracts, the entourage  of terpenes and phytocannabinoids can help create a more robust flavor profile. Expect a linear correlation between the effects and the taste when using Nano based products.

 Our products are shelf stable for 1 year and will remain as stable as the formulation they are infused into.  We recommend avoiding exposure of any cannabinoids to UV light as it can degrade the precious cannabis molecules. This is true with any active ingredients, Nano or oil based.  

FASTER ONSET & HIGHER EFFICACY

The formulations used by Splash Nano offer advantages for product formulators, and ultimately consumers, to deliver a higher portion of consumed active ingredients directly into the bloodstream and avoiding digestive degradation.  What this means is essentially the consumer is getting close to 100% of the active THC they are paying for. A direct effect of bioavailability is the enhanced permeation and retention effect (EPR).  This means that the consumer can start feeling therapeutic effects much faster than a standard oil formulation. All in all, more of the active is transferred to the bloodstream and achieved by a faster onset. 

NANO COSTS MORE PER MG THAN OIL BASED FORMULAS

But with Nano you actually need fewer milligrams (mg) to receive the same amount which in the end makes Nano products less expensive.

One of the most noticeable differences from the formulator’s standpoint is the price increase using a Nano-formulation VS using straight THC oil or distillate.  The ingredient costs can be 3-5x as much as using an inferior oil based product. The main reason for this is tremendous R&D costs, as well as excipient ingredients of the highest purity, and expensive machinery used to refine and further purify the active substances in the new Nano formulations.  The decision to switch to Nano may seem expensive, but the benefits far outweigh the initial upfront costs. Nearing 100% bioavailability, much faster onset, and the ability to work with water-based formulations are only a few of the obvious benefits.

WHAT ABOUT SOURCE MATERIALS?

Splash Nano proudly uses only the highest grade Full Spectrum cannabis extracts in our product formulations.  We also are proud to offer flexibility for brands dedicated to preserving the quality of their established supply chains and sources.